Biotinylated Human NPR2 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: NP2-H82E3
Physical State:: Liquid
Molecular Weight:: 52.2 kda
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: NPR2
Species:: Human
Uniprot:: P20594-1
Synonyms:: Atrial natriuretic peptide receptor type B;Guanylate cyclase B
Extra Details:: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]