NP2-H5253
Human NPR2 Protein, Mouse IgG2a Fc Tag
Cannot supply to this region.
- SKU:
- NP2-H5253
- Physical State:
- Powder
- Molecular Weight:
- 75.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.3
- Immunogen:
- NPR2
- Species:
- Human
- Uniprot:
- P20594-1
- Synonyms:
- Atrial natriuretic peptide receptor type B;Guanylate cyclase B
- Extra Details:
- This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Ambient