Human NK2R Full Length Protein (VLP)

Cannot supply to this region.

SKU:: NKR-H52P3
Physical State:: Liquid
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, Arginine, pH7.4
Immunogen:: NK2R
Species:: Human
Uniprot:: P21452
Synonyms:: neurokinin 2 receptor;neurokinin A receptor;neurokinin B receptor;NK-2 receptor;NK-2R;NK2R;NKNAR;seven transmembrane helix receptor;SKR;substance-K receptor;TAC2R;Tachykinin receptor 2
Extra Details:: NK2R is a G protein-coupled receptor with high affinity for the tachykinin Substance K (Neurokinin A). Upon activation, it triggers a phosphatidylinositol-calcium signaling pathway, leading to intracellular calcium release. The receptor's binding affinity follows the order: Substance K > Neuromedin K > Substance P. NK2R also regulates energy metabolism and has shown significant potential in appetite control. Due to its diverse functions, it is considered a promising therapeutic target for conditions such as asthma, irritable bowel syndrome, obesity, and type 2 diabetes.