NKD-C5248
Cynomolgus NKG2D / CD314 Protein, His Tag, low endotoxin
Cannot supply to this region.
- SKU:
- NKD-C5248
- Additional Names:
- CD314|KLRK1|NK cell receptor D|NKG2D
- Physical State:
- Powder
- Molecular Weight:
- 18.6 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- NKG2D
- Species:
- Non-human Primate
- Uniprot:
- P61252-1
- Synonyms:
- Killer cell lectin-like receptor subfamily K member 1;NK cell receptor D;NKG2-D-activating NK receptor
- Extra Details:
- NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them.
- Shipping Conditions:
- Ambient