Cynomolgus NKG2C / CD159c Protein, His Tag

Cannot supply to this region.

SKU:: NKC-C5247
Additional Names:: CD159c|KLRC2|NK cell receptor C|NKG2-C|NKG2C
Physical State:: Powder
Molecular Weight:: 17.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: NKG2C
Species:: Non-human Primate
Uniprot:: Q68VD0-1
Extra Details:: Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.