Human Nectin-4 Protein, His Tag (MALS verified)

Cannot supply to this region.

SKU:: NE4-H52H3
Additional Names:: LNIR|NECTIN4|PRR4|PVRL4
Physical State:: Powder
Molecular Weight:: 36.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Nectin-4
Species:: Human
Uniprot:: Q96NY8-1
Synonyms:: Ig superfamily receptor LNIR;Nectin cell adhesion molecule 4;Poliovirus receptor-related protein 4
Extra Details:: Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.