Human MUC-17 Protein, His Tag

Cannot supply to this region.

SKU:: MU7-H52H3
Additional Names:: MUC-17|MUC-3|MUC17|MUC3|Mucin-17
Physical State:: Powder
Molecular Weight:: 31.1 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: MUC-17
Species:: Human
Uniprot:: Q685J3-1
Synonyms:: Small intestinal mucin-3
Extra Details:: Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.