Biotinylated Human Mucin-1 (890-1158) Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: MU1-H82E5
Additional Names:: CA15-3|CD227|EMA|Episialin|H23AG|KL-6|MAM6|MUC-1|MUC1|Mucin 1|PEM|PEMT|PUM|SEC|X|ZD
Physical State:: Powder
Molecular Weight:: 21.3 kDa (partial A Alpha chain) & 10.2 kDa (partial B Beta chain)
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Mucin-1
Species:: Human
Uniprot:: P15941-1
Synonyms:: Breast carcinoma-associated antigen DF3;Cancer antigen 15-3;Carcinoma-associated mucin;Episialin;H23AG;Krebs von den Lungen-6;Peanut-reactive urinary mucin;PEMT;Polymorphic epithelial mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin
Extra Details:: Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.