Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag

Cannot supply to this region.

SKU:: MU1-H5153
Additional Names:: CA15-3|CD227|EMA|Episialin|H23AG|KL-6|MAM6|MUC-1|MUC1|Mucin 1|PEM|PEMT|PUM|SEC|X|ZD
Physical State:: Powder
Molecular Weight:: 32.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Immunogen:: Mucin-1
Species:: Human
Uniprot:: P15941-8
Synonyms:: Breast carcinoma-associated antigen DF3;Cancer antigen 15-3;Carcinoma-associated mucin;Episialin;H23AG;Krebs von den Lungen-6;Peanut-reactive urinary mucin;PEMT;Polymorphic epithelial mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin
Extra Details:: Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.