Human Mesothelin / MSLN (37-286) Protein, His Tag (MALS verified)

Cannot supply to this region.

SKU:: MSN-H5222
Additional Names:: Mesothelin|MPF|MSLN
Physical State:: Powder
Molecular Weight:: 27.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Mesothelin
Species:: Human
Extra Details:: Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.