Biotinylated Human MIF Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: MIF-H82E7
Additional Names:: GIF|GLIF|MIF|MMIF
Physical State:: Powder
Molecular Weight:: 16.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: 25 mM MES, 500 mM NaCl, pH6.5
Immunogen:: MIF
Species:: Human
Uniprot:: P14174-1
Synonyms:: Glycosylation-inhibiting factor;L-dopachrome isomerase;L-dopachrome tautomerase;Phenylpyruvate tautomerase
Extra Details:: Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.