LY5-H52H3
Human LY75 / CD205 Protein, His Tag
Cannot supply to this region.
- SKU:
- LY5-H52H3
- Additional Names:
- CD205|CLEC13B|DEC-205|gp200-MR6|LY75|Lymphocyte antigen 75
- Physical State:
- Powder
- Molecular Weight:
- 190.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- LY75
- Species:
- Human
- Uniprot:
- O60449-1
- Synonyms:
- C-type lectin domain family 13 member B;DEC-205;gp200-MR6
- Extra Details:
- lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.
- Shipping Conditions:
- Ambient