LR2-H5256
Human LRRC32 / GARP / Garpin Protein, Fc Tag (BLI verified)
Cannot supply to this region.
- SKU:
- LR2-H5256
- Additional Names:
- D11S833E|GARP|Garpin
- Physical State:
- Powder
- Molecular Weight:
- 92.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Immunogen:
- LRRC32
- Species:
- Human
- Uniprot:
- Q14392-1
- Synonyms:
- Garpin;Glycoprotein A repetitions predominant
- Extra Details:
- Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naive T cell proliferation.
- Shipping Conditions:
- Ambient