LO1-H5243
Human LOX-1 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- LO1-H5243
- Physical State:
- Powder
- Molecular Weight:
- 26.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- LOX-1
- Species:
- Human
- Uniprot:
- P78380-1
- Synonyms:
- C-type lectin domain family 8 member A;Lectin-like oxidized LDL receptor 1;Lectin-type oxidized LDL receptor 1
- Extra Details:
- LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.
- Shipping Conditions:
- Ambient