Biotinylated Human LILRA6 / CD85b / ILT8 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: LI6-H82E2
Additional Names:: CD85b|ILT-8|ILT8|LILRA6
Physical State:: Powder
Molecular Weight:: 50.0 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: LILRA6
Species:: Human
Uniprot:: Q6PI73-1
Synonyms:: Immunoglobulin-like transcript 8;Leukocyte Ig-like receptor
Extra Details:: The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 (ILT5) and LILRA6 (ILT8) are highly polymorphic receptors with similar extracellular domains. LILRA6 can signal through association with an activating adaptor molecule, FcRG Gamma, which bears a cytoplasmic tail with an immunoreceptor tyrosine-based activation motif. Analysis of mRNA expression in the major fractions of PBMCs showed that LILRA6 is primarily expressed in monocytes, and its expression level correlates with copy number of the gene.