Human LILRA3 / CD85e Protein, His Tag

Cannot supply to this region.

SKU:: LI3-H52H4
Additional Names:: CD85e|ILT6|LILRA3|LIR4
Physical State:: Powder
Molecular Weight:: 46.9 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: LILRA3
Species:: Human
Uniprot:: Q8N6C8-1
Synonyms:: CD85 antigen-like family member E;Immunoglobulin-like transcript 6;Leukocyte immunoglobulin-like receptor 4;Monocyte inhibitory receptor HM43/HM31
Extra Details:: Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) is also known as CD85 antigen-like family member E (CD85e), immunoglobulin-like transcript 6 (ILT-6), and leukocyte immunoglobulin-like receptor 4 (LIR-4) is a protein that in humans is encoded by the LILRA3 gene located within the eukocyte receptor complex on chromosome 19q13.4. Unlike many of its family, LILRA3 lacks a transmembrane domain, which contains 4 Ig-like C2-type (immunoglobulin-like) domains. LILRA3 acts as soluble receptor for class I MHC antigens. At the same time,LILRA3 can bind both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Also,LILRA3 can bind with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.