Human LILRA2 / CD85h / ILT1 Protein, His Tag

Cannot supply to this region.

SKU:: LI2-H52H3
Physical State:: Powder
Molecular Weight:: 48.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: LILRA2
Species:: Human
Uniprot:: Q8N149-1
Synonyms:: CD85 antigen-like family member H;Immunoglobulin-like transcript 1;Leukocyte immunoglobulin-like receptor 7
Extra Details:: LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7). It belongs to the subfamily A class of LIR receptors (LILRAs), which are single-pass type I transmembrane proteins with 2-4 extracellular Ig-like domains, a transmembrane domain (TM), and a short cytoplasmic tail. LILRA2 contains 4 Ig-like C2 type domains in the extracellular region. LILRA2 does not bind class I MHC antigens. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response.