Biotinylated Human LC3B Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: LCB-H81E4
Physical State:: Powder
Molecular Weight:: 18.1 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 20 mM Citric acid, 200 mM NaCl, pH3.5
Immunogen:: LC3B
Species:: Human
Uniprot:: Q9GZQ8
Synonyms:: ATG8F;Autophagy-related protein LC3 B;autophagy-related ubiquitin-like modifier LC3 B;LC3B;MAP1 light chain 3-like protein 2;MAP1A/1BLC3;MAP1A/MAP1B LC3 B;MAP1A/MAP1B light chain 3 B;MAP1LC3B-a;Microtubule-associated protein 1 light chain 3 beta;microtubule-associated proteins 1A/1B light chain 3B
Extra Details:: LC3B is a pivotal protein encoded by the MAP1LC3B gene, widely recognized as a core component and indicator of cellular autophagy. It plays an essential role in autophagosome formation and the regulation of the autophagic degradation pathway. Critically, the conversion of cytosolic LC3B-I to lipidated, autophagosome-associated LC3B-II upon autophagy activation serves as a robust and widely used biochemical hallmark for assessing autophagic activity.