Human Laminin 211 Protein, premium grade

Cannot supply to this region.

SKU:: LA8-H5263
Physical State:: Powder
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: Laminin 211
Species:: Human
Extra Details:: Laminin-A Alpha2 is a critical component of the laminin heterotrimer, which along with laminin-B Beta1 or B Beta2 and laminin-G Gamma1 form the structural glycoproteins laminin-211 and laminin-221 in skeletal muscle. Laminin-211 is the most abundant laminin isoform in the basement membrane of adult skeletal muscle. Laminin-211 and -221 polymerize with each other and interact with nidogen and collagen-IV to form the muscle basal lamina. Laminin-211 and laminin-221 bind to muscle cell surface through the A Alpha7B Beta1 integrin and A Alpha-dystroglycan of the dystrophin glycoprotein complex via their globular C-terminal domains.