LA2-H5269
Human Laminin 221 Protein, premium grade
Cannot supply to this region.
- SKU:
- LA2-H5269
- Additional Names:
- Laminin 221 E8
- Physical State:
- Powder
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- Laminin 221
- Species:
- Human
- Extra Details:
- Laminin-221 (LM221) takes multiple roles as a scaffold to store cells, growth factors and cytokines and is the most likely expressed cardiac laminin that maintains physiological activities of myocytes. Laminin 221-E8 consists of the C-terminal end of the alpha 2, beta 2, and gamma 1 chains. Previous study has confirmed that the laminin-221 heterotrimer (A Alpha2B Beta2G Gamma1) could bind integrin A Alpha7X1 and A Alpha7X2. Latest research indicated that the administration of LM221 enhanced accumulation of smooth muscle actin (SMA) and isolectin B4 (ILB4) double-positive cells to the damaged area and contributed to the improvement of cardiac function.
- Shipping Conditions:
- Ambient





