KR1-H5253
Human Kremen-1 protein, Fc Tag
Cannot supply to this region.
- SKU:
- KR1-H5253
- Additional Names:
- KREMEN|Kringle domain-containing transmembrane protein 1|Kringle-containing protein marking the eye and the nose|KRM1, Dickkopf receptor
- Physical State:
- Powder
- Molecular Weight:
- 67.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- KREMEN1
- Species:
- Human
- Uniprot:
- Q96MU8-1
- Synonyms:
- Dickkopf receptor;Kringle domain-containing transmembrane protein 1;Kringle-containing protein marking the eye and the nose
- Extra Details:
- Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/B Beta-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
- Shipping Conditions:
- Ambient