Biotinylated Human KIR3DL3 / CD158z Protein, Fc,Avitag[TM]

Cannot supply to this region.

SKU:: KI3-H82F3
Physical State:: Powder
Molecular Weight:: 60.4 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, pH7.4, 25mM Arginine
Immunogen:: KIR3DL3
Species:: Human
Uniprot:: Q8N743-1
Synonyms:: CD158 antigen-like family member Z;Killer cell inhibitory receptor 1
Extra Details:: the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [