Human TIM-1 / KIM-1 / HAVCR1 Protein, His Tag (MALS verified)

Cannot supply to this region.

SKU:: KI1-H52H3
Additional Names:: HAVCR1|KIM1|TIM1|TIMD1
Physical State:: Powder
Molecular Weight:: 31.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: TIM-1
Species:: Human
Uniprot:: Q96D42-1
Synonyms:: Kidney injury molecule 1;T-cell immunoglobulin and mucin domain-containing protein 1;T-cell immunoglobulin mucin receptor 1;T-cell membrane protein 1
Extra Details:: Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.