KI1-H5255
Human KIR2DL1 / CD158a / NKAT-1 Protein, Fc Tag
Cannot supply to this region.
- SKU:
- KI1-H5255
- Additional Names:
- CD158a
- Physical State:
- Powder
- Molecular Weight:
- 50.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- KIR2DL1
- Species:
- Human
- Uniprot:
- P43626-1
- Synonyms:
- CD158 antigen-like family member A;MHC class I NK cell receptor;Natural killer-associated transcript 1;p58 natural killer cell receptor clones CL-42/47.11;p58.1 MHC class-I-specific NK receptor
- Extra Details:
- Killer cell immunoglobulin-like receptor 2DL1(KIR2DL1), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells. Regulation of NK cell activity is mediated through killer-cell immunoglobulin-like receptors (KIR) ability to recognize human leukocyte antigen (HLA) class I molecules as ligands. Interaction of KIR and HLA is implicated in viral infections, autoimmunity, and reproduction and there is growing evidence of the coevolution of these two independently segregating gene families. Association of KIR2DL1 with B Beta-arrestin 2 mediated recruitment of the tyrosine phosphatases SHP-1 and SHP-2 to KIR2DL1 and facilitated downstream inhibitory signaling.
- Shipping Conditions:
- Ambient