Human Kallikrein 7 Protein, Tag Free, low endotoxin (active enzyme)

Cannot supply to this region.

SKU:: KA7-H5213
Physical State:: Liquid
Molecular Weight:: 24.3 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 20 mM HEPES, 150 mM NaCl, pH7.5
Immunogen:: Kallikrein 7
Species:: Human
Uniprot:: P49862-1
Synonyms:: Serine protease 6;Stratum corneum chymotryptic enzyme
Extra Details:: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]