Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

Cannot supply to this region.

SKU:: IT1-R53WB
Physical State:: Powder
Molecular Weight:: 113.4 kDa & 83.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: Integrin alpha 3 beta 1
Species:: Rat
Uniprot:: I4DUB5, P49134
Synonyms:: beta OL;beta oligodendroglia;collagen alpha-1(I) chain-like;fibronectin receptor subunit beta;integrin beta 1 (fibronectin receptor beta);integrin beta-1;integrin VLA-4 subunit beta;VLA-4 subunit beta
Extra Details:: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.