IT1-H52WC
Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free, low endotoxin (MALS verified)
Cannot supply to this region.
- SKU:
- IT1-H52WC
- Additional Names:
- Integrin alpha 3 beta 1|ITGA3&ITGB1
- Physical State:
- Powder
- Molecular Weight:
- 113.3 kDa (ITGA3) & 83.7 kDa (ITGB1)
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 0.2 M Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- Integrin alpha 3 beta 1
- Species:
- Human
- Uniprot:
- P05556-1, P26006-2
- Synonyms:
- CD49 antigen-like family member C;Fibronectin receptor subunit beta;FRP-2;Galactoprotein B3;Glycoprotein IIa;VLA-3 subunit alpha;VLA-4 subunit beta
- Extra Details:
- Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
- Shipping Conditions:
- Ambient