IT1-H52W8
Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, His Tag&Tag Free
Cannot supply to this region.
- SKU:
- IT1-H52W8
- Additional Names:
- Integrin isoform alpha-7X2B beta 1|ITGA7X2B&ITGB1|ITGA7X2BB1
- Physical State:
- Powder
- Molecular Weight:
- 116.5 kDa (ITGA7X2B) & 83.7 kDa (ITGB1)
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 150 mM NaCl, pH7.5
- Immunogen:
- Integrin isoform alpha-7X2B beta 1
- Species:
- Human
- Uniprot:
- P05556-1, Q13683-7
- Synonyms:
- Fibronectin receptor subunit beta;Glycoprotein IIa;VLA-4 subunit beta
- Extra Details:
- Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.
- Shipping Conditions:
- Ambient