Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: IN4-H52W3
Physical State:: Powder
Molecular Weight:: 116.8 kDa | 81.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, 0.2 M Arginine, pH7.5
Immunogen:: Integrin alpha 6 beta 4
Species:: Human
Uniprot:: P16144-2, P23229-2
Synonyms:: CD49 antigen-like family member F;GP150;VLA-6
Extra Details:: Integrin A Alpha6B Beta4 is a key laminin receptor predominantly found in stratified squamous epithelia, especially localized to hemidesmosomes in the basal epidermal layer, where it plays a crucial role in cell-basement membrane adhesion, regulation of keratinocyte motility and polarity, and contributes to the structure of hemidesmosomal plaques, distinguishing it from other integrins.