Biotinylated Human IL-2 R gamma / CD132 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: ILG-H85E8
Additional Names:: CD132|CIDX|gammaC|IL2RG|IMD4|P64|SCIDX|SCIDX1
Physical State:: Powder
Molecular Weight:: 31.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IL-2 R gamma
Species:: Human
Uniprot:: P31785-1
Synonyms:: gammaC;Interleukin-2 receptor subunit gamma;p64
Extra Details:: IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as A Alpha, B Beta and G Gamma, which are non-covalently associated are identified. The A Alpha and B Beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the G Gamma chain, along with the B Beta subunit. The A Alpha chain of the IL-2R can bind to the B Beta chain before receptor interaction with IL-2. The G Gamma chain alone has a very weak affinity for IL-2, but after the ligand is bound to the A Alpha/B Beta heterodimer, the G Gamma chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).

Shipping Conditions:: Ambient