Human IL-17 RC (21-465) Protein, Fc Tag (MALS verified)

Cannot supply to this region.

SKU:: ILC-H5258
Physical State:: Powder
Molecular Weight:: 76 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Immunogen:: IL-17 RC
Species:: Human
Extra Details:: Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.