Biotinylated Mouse IL-17B Protein, Fc,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: ILB-M82F3
Physical State:: Powder
Molecular Weight:: 46.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IL-17B
Species:: Mouse
Uniprot:: Q9QXT6
Synonyms:: 1110006O16Rik;1700006N07Rik;cytokine CX1;cytokine-like protein ZCYTO7;gene for cytokine-like protein;IL-17B;interleukin-17B;neuronal interleukin-17-related factor;Zcyto;Zcyto7
Extra Details:: IL-17B is a member of IL17 famaily, was originally described as a proinflammatory cytokine. IL-17B is produced by neutrophils and potentiates TNF-A Alpha effect on the production of cytokines and chemokines, such as IL-6, G-CSF, and CCL20, known to control immune cell trafficking to inflamed tissues. Interestingly, although IL-17B and IL-17E (IL-25) share a common receptor, IL-17RB, IL-17B, and IL-17E deficiency lead to opposite results in a model of acute colitis induced by dextran sulfate sodium. IL-17B inhibits IL-17E binding to IL-17RA- IL-17RB complexes on epithelial cells, and limits IL-17E-induced IL-6 production by colon epithelial cells.