Mouse IL-2 R beta / CD122 Protein, Fc Tag

Cannot supply to this region.

SKU:: ILB-M5253
Additional Names:: CD122|IL2RB|P70-75|RP5-1170K4.6
Physical State:: Powder
Molecular Weight:: 51.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Immunogen:: IL-2 R beta
Species:: Mouse
Uniprot:: P16297-1
Synonyms:: High affinity IL-2 receptor subunit beta;p70-75
Extra Details:: Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - A Alpha (CD25), B Beta (CD122) and G Gamma (CD132) - non-covalently associating. The A Alpha and B Beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the G Gamma-chain, along with the B Beta subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.