ILB-H5219
Human IL-23 alpha & IL-12 beta Heterodimer Protein, premium grade
Cannot supply to this region.
- SKU:
- ILB-H5219
- Physical State:
- Powder
- Molecular Weight:
- 55.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- IL23A & IL12B
- Species:
- Human
- Uniprot:
- P29460-1, Q9NPF7-1
- Synonyms:
- Cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p40;Interleukin-23 subunit p19;NK cell stimulatory factor chain 2
- Extra Details:
- Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Shipping Conditions:
- Ambient