Rat IL-17A / CTLA-8 Protein, His Tag (MALS verified)

Cannot supply to this region.

SKU:: ILA-R5243
Physical State:: Powder
Molecular Weight:: 16.9 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IL-17A
Species:: Rat
Uniprot:: Q61453
Synonyms:: Cytotoxic T-lymphocyte-associated antigen 8
Extra Details:: Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8), which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-K KappaB and mitogen-activated protein kinases. Also, IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). Furthermore, IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.