ILA-M52H6
Mouse IL-17 RA / CD217 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- ILA-M52H6
- Physical State:
- Powder
- Molecular Weight:
- 35.2 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- IL-17 RA
- Species:
- Mouse
- Uniprot:
- Q60943
- Synonyms:
- AW538159;Cdw217;Il;IL-17 receptor A;IL-17RA;Il17r;interleukin-17 receptor A;VDw21;VDw217
- Extra Details:
- Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
- Shipping Conditions:
- Ambient