ILA-H5222
Human IL-17 RA / CD217 Protein, His Tag
Cannot supply to this region.
- SKU:
- ILA-H5222
- Additional Names:
- CANDF5|CD217|CDw217|hIL-17R|IL-17RA|IL17R
- Physical State:
- Powder
- Molecular Weight:
- 34.3 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- IL-17 RA
- Species:
- Human
- Uniprot:
- Q96F46-1
- Synonyms:
- CDw217
- Extra Details:
- Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
- Shipping Conditions:
- Ambient