IL8-M51H3
Mouse IL-18 Protein, His Tag
Cannot supply to this region.
- SKU:
- IL8-M51H3
- Physical State:
- Powder
- Molecular Weight:
- 20.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- IL-18
- Species:
- Mouse
- Uniprot:
- P70380
- Synonyms:
- IFN-gamma-inducing factor;Ig;Igif;Il-;IL-1 gamma;Il-18;interferon gamma-inducing factor;interleukin-1 gamma;interleukin-18
- Extra Details:
- Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-gamma (IFN-gamma) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL-12. IL-18 also functions in developmental regulation of T-lymphocyte helper type I cells and in Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. It acts by inducing heterodimerization of the two subunits of its receptor, IL-18RAlpha and IL-18RBeta shows structural similarity to IL-1.
- Shipping Conditions:
- Ambient