Human IL-8 / CXCL8 Protein, premium grade

Cannot supply to this region.

SKU:: IL8-H5217
Physical State:: Powder
Molecular Weight:: 8.4 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: IL-8
Species:: Human
Uniprot:: P10145-1
Synonyms:: C-X-C motif chemokine 8;Chemokine (C-X-C motif) ligand 8;Emoctakin;Granulocyte chemotactic protein 1;Monocyte-derived neutrophil chemotactic factor;Monocyte-derived neutrophil-activating peptide;Neutrophil-activating protein 1;Protein 3-10C;T-cell chemotactic factor
Extra Details:: Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.