Biotinylated Mouse IL-4 Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: IL4-M82E3
Physical State:: Powder
Molecular Weight:: 17.1 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IL-4
Species:: Mouse
Uniprot:: P07750
Synonyms:: B-cell growth factor 1;B-cell IgG differentiation factor;B-cell stimulatory factor 1;BSF-1;IGG1 induction factor;Il;Il-4;interleukin-4;lymphocyte stimulatory factor 1
Extra Details:: Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.