IL3-M5245
Mouse IL-33 Protein, His Tag
Cannot supply to this region.
- SKU:
- IL3-M5245
- Additional Names:
- C9ORF26|DKFZp586H0523|DV27|DVS27|IL1F11|IL33|NFEHEV|NFHEV|RP11-575C20.2
- Physical State:
- Powder
- Molecular Weight:
- 19.6 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- IL-33
- Species:
- Mouse
- Uniprot:
- Q8BVZ5-1
- Extra Details:
- Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-K KappaB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
- Shipping Conditions:
- Ambient