Mouse IL-12B&IL-12A Heterodimer Protein, Tag Free&His Tag (MALS verified)

Cannot supply to this region.

SKU:: IL2-M52W3
Physical State:: Powder
Molecular Weight:: 35.8 kDa & 23.6 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IL-12B & IL-12A
Species:: Mouse
Uniprot:: P43431, P43432
Synonyms:: CLMF p35;CLMF p40;cytotoxic lymphocyte maturation factor 35 kDa subunit;cytotoxic lymphocyte maturation factor 40 kDa subunit;Il-1;IL-12;IL-12 p35 subunit;IL-12 p40 subunit;IL-12 subunit p35;IL-12 subunit p40;Il-12a;Il-12b;IL-12p35;Il-12p40;IL-23 subunit p40;Il12p40;interleukin 12a p35 subunit;interleukin-12 p35 subunit;interleukin-12 p40 subunit;interleukin-12 subunit alpha;interleukin-12 subunit beta;Ll12a;p3;p35;p40
Extra Details:: Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-G Gamma and TNF-A Alpha from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-G Gamma. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.