Biotinylated Human IL-22 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: IL2-H8247
Additional Names:: IL-22|IL-TIF|ZCYTO18
Physical State:: Powder
Molecular Weight:: 20.3 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: IL-22
Species:: Human
Uniprot:: Q9GZX6-1
Synonyms:: Cytokine Zcyto18;IL-10-related T-cell-derived-inducible factor
Extra Details:: Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.