Human IL-12 Protein, premium grade

Cannot supply to this region.

SKU:: IL2-H5210
Additional Names:: IL12|Interleukin-12|p70
Physical State:: Powder
Molecular Weight:: 58.9 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: IL-12B & IL-12A
Species:: Human
Uniprot:: P29459-1, P29460-1
Synonyms:: Cytotoxic lymphocyte maturation factor 35 kDa subunit;Cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p35;IL-12 subunit p40;NK cell stimulatory factor chain 1;NK cell stimulatory factor chain 2
Extra Details:: Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-G Gamma and TNF-A Alpha from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-G Gamma. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.