IL1-H5219
Human IL-31 Protein, premium grade
Cannot supply to this region.
- SKU:
- IL1-H5219
- Physical State:
- Powder
- Molecular Weight:
- 15.8 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- IL-31
- Species:
- Human
- Uniprot:
- Q6EBC2-1
- Extra Details:
- IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor B Beta (OSMRB Beta) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
- Shipping Conditions:
- Ambient