Biotinylated Mouse IgG2a Fc Protein, Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: IGA-M8210
Additional Names:: IgG2A
Physical State:: Powder
Molecular Weight:: 28.2 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: Tris with Glycine, Arginine and NaCl, pH7.5
Immunogen:: IgG2a Fc
Species:: Mouse
Uniprot:: P01863
Synonyms:: Immunoglobulin heavy chain gamma polypeptide
Extra Details:: Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-G Gamma (IgG) antibody molecules changes in rheumatoid arthritis.