Human IFN-beta Protein, Fc Tag (MALS verified)

Cannot supply to this region.

SKU:: IFB-H5254
Physical State:: Powder
Molecular Weight:: 46.5 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: IFN-beta
Species:: Human
Uniprot:: P01574
Synonyms:: fibroblast interferon;IFB;IFF;IFN-beta;IFNB;interferon beta;interferon-beta;interferon, beta 1, fibroblast
Extra Details:: Interferon beta(IFN beta) is type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity)