IF2-H5224
Human IFN-alpha/beta R2 Protein, (MALS & BLI verified)
Cannot supply to this region.
- SKU:
- IF2-H5224
- Additional Names:
- beta receptor 2|IFN-alpha|IFN-R-2|IFNABR|IFNAR2|IFNARB
- Physical State:
- Powder
- Molecular Weight:
- 25.8 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- IFN-alpha/beta R2
- Species:
- Human
- Uniprot:
- P48551-2
- Synonyms:
- Interferon alpha binding protein;Type I interferon receptor 2
- Extra Details:
- Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.
- Shipping Conditions:
- Ambient