ID1-H5143
Human IDO1 Protein, His Tag (active enzyme, MALS verified)
Cannot supply to this region.
- SKU:
- ID1-H5143
- Physical State:
- Liquid
- Molecular Weight:
- 47.2 kda
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 20 mM Tris, 300 mM NaCl, pH7.5
- Immunogen:
- IDO1
- Species:
- Human
- Uniprot:
- P14902-1
- Synonyms:
- Indoleamine-pyrrole 2,3-dioxygenase
- Extra Details:
- This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Shipping Conditions:
- Dry Ice