ICS-M5259
Mouse ICOS / CD278 (C137S, C138S) Protein, Fc Tag
Cannot supply to this region.
- SKU:
- ICS-M5259
- Additional Names:
- AILIM|CD278|ICOS|Inducible T-cell costimulator
- Physical State:
- Powder
- Molecular Weight:
- 40.6 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Immunogen:
- ICOS
- Species:
- Mouse
- Uniprot:
- Q9WVS0-1
- Synonyms:
- Activation-inducible lymphocyte immunomediatory molecule;CD28 and CTLA-4-like protein;CD28-related protein 1
- Extra Details:
- Inducible T-cell costimulator (ICOS) is also known as Activation-inducible lymphocyte immunomediatory molecule (AILIM), CD278, which belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. ICOS enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. CD278 / ICOS prevents the apoptosis of pre-activated T-cells and also plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Shipping Conditions:
- Ambient